| Gene Symbol | B4GALT2 |
|---|---|
| Entrez Gene | 8704 |
| Alt Symbol | B4Gal-T2, B4Gal-T3, beta4Gal-T2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| Other Description | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2|UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2|UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2|UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2|beta-1,4-GalTase 2|beta-1,4-galactosyltransferase 2|beta-4-GalT2|beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2 |
| Swissprots | Q9NSY7 B3KTP0 Q9BUP6 D3DPY6 Q5T4Y5 B4DE14 Q4V9L9 O60909 D3DPY7 O60511 Q5T4X5 |
| Accessions | EAX07062 EAX07063 EAX07064 EAX07065 O60909 AB024434 BAA75819 AF038660 AAC39733 AI702508 AK074533 BAG51967 AK095873 BAG53152 AK293418 BAG56925 AL137647 CAB70857 AL535811 BC002431 BC096821 AAH96821 BQ222671 CD675528 DC386748 Y12510 CAA73112 NM_001005417 NP_001005417 NM_003780 NP_003771 NM_030587 NP_085076 |
| Function | Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. |
| Tissue Specificity | Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain. |
| Top Pathways | N-Glycan biosynthesis, Other types of O-glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Galactose metabolism, Glycosphingolipid biosynthesis - lacto and neolacto series |