| Gene Symbol | POLR2H |
|---|---|
| Entrez Gene | 5437 |
| Alt Symbol | RPABC3, RPB17, RPB8 |
| Species | Human |
| Gene Type | protein-coding |
| Description | polymerase (RNA) II (DNA directed) polypeptide H |
| Other Description | DNA-directed RNA polymerase II subunit H|DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide|DNA-directed RNA polymerases I, II, and III subunit RPABC3|RPB8 homolog |
| Swissprots | Q969R0 C9JBJ6 P53802 C9JCU7 P52434 C9JUA8 C9J413 |
| Accessions | CAB92189 EAW78246 EAW78247 P52434 AA431357 AI244238 BC000739 AAH00739 BG529732 BI603667 BM541682 BQ065952 BX283032 CN368789 EU446997 ABZ92526 HY164762 HY178178 U37689 AAA91458 Z49199 CAA89060 XM_005247541 XP_005247598 XM_006713666 XP_006713729 XM_006713667 XP_006713730 XM_006713668 XP_006713731 XM_006713670 XP_006713733 NM_001278698 NP_001265627 NM_001278699 NP_001265628 NM_001278700 NP_001265629 NM_001278714 NP_001265643 NM_001278715 NP_001265644 NM_006232 NP_006223 |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. {ECO:0000269|PubMed:9852112}. |
| Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:9852112, ECO:0000269|Ref.6}. |
| Top Pathways | Huntington's disease, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase |