ASNA1

Gene Symbol	ASNA1
Entrez Gene	439
Alt Symbol	ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I
Species	Human
Gene Type	protein-coding
Description	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Other Description	ATPase ASNA1|golgi to ER traffic 3 homolog|transmembrane domain recognition complex 40 kDa ATPase subunit|transmembrane domain recognition complex, 40kDa
Swissprots	O43681 A6NHP8 Q53FC6 A8K740 Q92849
Accessions	AAP45050 EAW84303 O43681 AF047469 AAC03551 AK223363 BAD97083 AK291855 BAF84544 AK293588 BAG57056 BC002651 AAH02651 BG426136 JF432148 ADZ15365 U60276 AAC50731 NM_004317 NP_004308
Function	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling. {ECO:0000255|HAMAP-Rule:MF_03112, ECO:0000269|PubMed:17382883, ECO:0000269|PubMed:18477612}.
Subcellular Location	Cytoplasm. Endoplasmic reticulum. Nucleus, nucleolus.
Tissue Specificity	Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle. {ECO:0000269|PubMed:9774623}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ARSA (H-7) - sc-390568 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

ARSA (L-20) - sc-28126 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ARSA (H-161) - sc-366535 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

ARSA (K-18) - sc-28128 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ARSA (7A) - sc-100676 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-ASNA1 antibody - ab54843 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-ASNA1 antibody - ab96388 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 antibody [EPR11422] - ab169549 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR11422

Anti-ASNA1 antibody [EPR11423] - ab169539 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR11423

Anti-ASNA1 Antibody (Internal) - LS-C87255 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, AP) - LS-C251790 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa218-267) - LS-C135738 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, APC) - LS-C251791 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, Biotin) - LS-C251792 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, FITC) - LS-C251793 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, Azide-free, HRP) - LS-C251794 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312, PE) - LS-C251795 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (C-Terminus) - LS-C135739 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312) - LS-C319616 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa283-312) - LS-C159125 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (aa45-279) - LS-C186356 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ASNA1 Antibody (clone 2H3) - LS-C133055 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2H3

ASNA1 Antibody (2H3) - H00000439-M03 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2H3

ASNA1 Antibody (5A3) - H00000439-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5A3

ASNA1 Antibody - NBP2-14324 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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