ASNA1

Gene Symbol	ASNA1
Entrez Gene	439
Alt Symbol	ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I
Species	Human
Gene Type	protein-coding
Description	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Other Description	ATPase ASNA1|golgi to ER traffic 3 homolog|transmembrane domain recognition complex 40 kDa ATPase subunit|transmembrane domain recognition complex, 40kDa
Swissprots	O43681 A6NHP8 Q53FC6 A8K740 Q92849
Accessions	AAP45050 EAW84303 O43681 AF047469 AAC03551 AK223363 BAD97083 AK291855 BAF84544 AK293588 BAG57056 BC002651 AAH02651 BG426136 JF432148 ADZ15365 U60276 AAC50731 NM_004317 NP_004308
Function	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling. {ECO:0000255|HAMAP-Rule:MF_03112, ECO:0000269|PubMed:17382883, ECO:0000269|PubMed:18477612}.
Subcellular Location	Cytoplasm. Endoplasmic reticulum. Nucleus, nucleolus.
Tissue Specificity	Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle. {ECO:0000269|PubMed:9774623}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ASNA1 full length protein - ab134590 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

ASNA1 Antibody Blocking Peptide - LS-E5600 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ASNA1 Antibody Blocking Peptide - LS-E22038 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ASNA1 Antibody Blocking Peptide - LS-E22039 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ASNA1 Antibody Blocking Peptide - LS-E26681 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ASNA1 Recombinant Protein - H00000439-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

ASNA1 Partial Recombinant Protein - H00000439-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ASNA1 Protein - NBP2-22694 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

ARSA-Antibody-C-term-Blocking-Peptide - BP18128b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ASNA1 blocking peptide - GTX88779-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

Human ASNA1 protein - orb244033 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human ASNA1 protein - orb167935 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

ASNA1 Blocking Peptide - 33R-4797 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ASNA1 Blocking Peptide - 33R-2281 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ASNA1 protein (His tag) - 80R-2503 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

ASNA1 Peptide - AC21-1522-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ASNA1 / ARSA (1-348, His-tag) - AR50575PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ASNA1 / ARSA (1-348, His-tag) - AR50575PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ASNA1 / ARSA - H00000439-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

ASNA1 / ARSA - H00000439-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ASNA1 / ARSA - H00000439-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ASNA1, 1-348aa, Human, His tag, E.coli - 01-P1751 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ASNA1 Peptide - 46-813P from ProSci Category Peptide Species Human, Mouse, Rat

ASNA1 fusion protein - Ag7936 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ASNA1 fusion protein - Ag7713 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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