Gene Symbol |
Aox2
|
Entrez Gene |
213043
|
Alt Symbol |
Aoh3, Aox3l1
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
aldehyde oxidase 2
|
Other Description |
aldehyde oxidase 3-like 1|aldehyde oxidase homolog 3|aldehyde oxidase-like protein 3|azaheterocycle hydroxylase 2
|
Swissprots |
Q5SGK3 B9EKC6
|
Accessions |
EDL00071 Q5SGK3 AY187018 AAO38750 AY665589 AAV68256 BC150826 AAI50827 XM_006495829 XP_006495892 NM_001008419 NP_001008419
|
Function |
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as phthalazine, as well as aldehydes, such as benzaldehyde and retinal. Cannot use hypoxanthine as substrate. {ECO:0000269|PubMed:15383531}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15383531}.
|
Tissue Specificity |
Expressed in olfactory mucosa epithelium (at protein level). Detected in skin. {ECO:0000269|PubMed:15383531, ECO:0000269|PubMed:23263164}.
|
Top Pathways |
Tyrosine metabolism, Vitamin B6 metabolism, Nicotinate and nicotinamide metabolism, Retinol metabolism, Tryptophan metabolism
|