Gene Symbol | COL4A3BP |
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Entrez Gene | 10087 |
Alt Symbol | CERT, CERTL, GPBP, STARD11 |
Species | Human |
Gene Type | protein-coding |
Description | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
Other Description | StAR-related lipid transfer (START) domain containing 11|ceramide transfer protein|ceramide transporter|collagen type IV alpha-3-binding protein|hCERT|lipid-transfer protein CERTL |
Swissprots | Q9H2S7 Q96Q85 A8K7S2 Q9H2S8 Q53YV1 Q9Y5P4 Q53YV2 Q96Q88 B3KUB7 |
Accessions | AAG42051 BAB58974 BAB58977 CAH23431 CAH23432 EAW95757 EAW95758 EAW95759 EAW95760 EAW95761 Q9Y5P4 AF136450 AAD30288 AF232930 AAG42046 AK000604 AK091851 BAC03762 AK096854 BAG53379 AK125387 AK292087 BAF84776 AY453385 AAR26717 AY453386 AAR26718 BC000102 AAH00102 XM_006714513 XP_006714576 XM_011543090 XP_011541392 XM_011543091 XP_011541393 NM_001130105 NP_001123577 NM_005713 NP_005704 NM_031361 NP_112729 |
Function | Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. {ECO:0000269|PubMed:14685229, ECO:0000269|PubMed:17591919, ECO:0000269|PubMed:18184806, ECO:0000269|PubMed:20036255}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806}. Golgi apparatus {ECO:0000269|PubMed:14685229, ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806}. Endoplasmic reticulum {ECO:0000269|PubMed:16895911, ECO:0000269|PubMed:18184806}. Note=Preferentially localized to the Golgi apparatus. {ECO:0000305|PubMed:16895911}. |
Tissue Specificity | Widely expressed. |
GPBP CRISPR/Cas9 KO Plasmid (h) - sc-408465 from Santa Cruz Biotechnology
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GPBP HDR Plasmid (h) - sc-408465-HDR from Santa Cruz Biotechnology
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GPBP Double Nickase Plasmid (h) - sc-408465-NIC from Santa Cruz Biotechnology
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GPBP Double Nickase Plasmid (h2) - sc-408465-NIC-2 from Santa Cruz Biotechnology
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GPBP CRISPR Activation Plasmid (h) - sc-408465-ACT from Santa Cruz Biotechnology
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GPBP CRISPR Activation Plasmid (h2) - sc-408465-ACT-2 from Santa Cruz Biotechnology
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GPBP Lentiviral Activation Particles (h) - sc-408465-LAC from Santa Cruz Biotechnology
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GPBP Lentiviral Activation Particles (h2) - sc-408465-LAC-2 from Santa Cruz Biotechnology
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GPBP siRNA (h) - sc-62395 from Santa Cruz Biotechnology
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GPBP shRNA Plasmid (h) - sc-62395-SH from Santa Cruz Biotechnology
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GPBP shRNA (h) Lentiviral Particles - sc-62395-V from Santa Cruz Biotechnology
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COL4A3BP RNAi - H00010087-R04 from Novus Biologicals
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COL4A3BP RNAi - H00010087-R03 from Novus Biologicals
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MISSION® esiRNA - EHU069681 from Sigma-Aldrich
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MISSION® siRNA - SIHK0481 from Sigma-Aldrich
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MISSION® siRNA - SIHK0483 from Sigma-Aldrich
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MISSION® siRNA - SIHK0482 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6392 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6392 from Sigma-Aldrich
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COL4A3BP siRNA (Human) - CRH6797 from Cohesion Biosciences
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COL4A3BP - MBS8233249 from MyBioSource
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shRNA set against Human COL4A3BP (NM_005713.2) - SHH267297 from Creative biogene
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COL4A3BP shRNA Plasmid (Human) - CHH6797 from Cohesion Biosciences
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COL4A3BP miRNA 3'UTR clone - MiUTR4H-TG02253 from Creative biogene
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