Gene Symbol | PPP1R12C |
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Entrez Gene | 54776 |
Alt Symbol | LENG3, MBS85, p84, p85 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory subunit 12C |
Other Description | leukocyte receptor cluster (LRC) encoded novel gene 3|leukocyte receptor cluster (LRC) member 3|myosin-binding subunit 85|protein phosphatase 1 myosin-binding subunit of 85 kDa|protein phosphatase 1 myosin-binding subunit p85|protein phosphatase 1 regulatory subunit 12C|protein phosphatase 1, regulatory (inhibitor) subunit 12C |
Swissprots | Q96HW1 Q7L8F7 Q9H5H5 B4DME2 Q9NT00 Q6ZPD1 Q59FK8 Q9BZL4 |
Accessions | EAW72332 EAW72333 EAW72334 EAW72335 Q9BZL4 AA551617 AB209452 BAD92689 AF211968 AF312028 AAG60045 AK027086 BAB15651 AK129529 BAC85179 AK297187 BAG59676 AK297426 BAG59854 AL137618 CAB70844 BC008030 AAH08030 BC010628 BC156295 AAI56296 HY013088 XM_005259013 XP_005259070 XM_011527045 XP_011525347 XR_935836 NM_001271618 NP_001258547 NM_017607 NP_060077 |
Function | Regulates myosin phosphatase activity. {ECO:0000269|PubMed:11399775}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments and stress fibers. {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in heart. {ECO:0000269|PubMed:11399775}. |
Top Pathways | Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, Proteoglycans in cancer, Regulation of actin cytoskeleton |
PPP1R12C / MBS85 Antibody Blocking Peptide - LS-E24501 from LifeSpan Bioscience
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PPP1R12C fusion protein - ag18559 from Proteintech Group
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PPP1R12C fusion protein - ag18558 from Proteintech Group
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Recombinant Human PPP1R12C - PPP1R12C-1178H from Creative Biomart
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Recombinant Human Protein phosphatase 1 regulatory subunit 12C(PPP1R12C) - CSB-YP871627HU CSB-EP871627HU CSB-BP871627HU CSB-MP871627HU from Cusabio
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PPP1R12C Protein - NBP1-94079PEP from Novus Biologicals
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PPP1R12C Peptide, Human - M34GP12233H from Creative Peptides
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PPP1R12C fusion protein - Ag26015 from Proteintech Group
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Protein phosphatase 1 regulatory subunit 12C (PPP1R12C), Recombinant Protein - MBS1343254 from MyBioSource
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