Gene Symbol | KCNH8 |
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Entrez Gene | 131096 |
Alt Symbol | ELK, ELK1, Kv12.1, elk3 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated eag related subfamily H, member 8 |
Other Description | ELK channel 3|ether-a-go-go-like potassium channel 1|ether-a-go-go-like potassium channel 3|hElk1|potassium voltage-gated channel subfamily H member 8|potassium voltage-gated channel, subfamily H (eag-related), member 8|voltage-gated potassium channel subunit Kv12.1 |
Swissprots | B7Z2I7 Q96L42 Q59GQ6 |
Accessions | EAW64296 EAW64297 Q96L42 AB209053 BAD92290 AK294417 BAH11759 AK294759 BAH11873 AK295633 BAH12134 AK309034 AY053503 AAL15429 BC031226 BC152893 AAI52894 XM_011533343 XP_011531645 XM_011533344 XP_011531646 XM_011533345 XP_011531647 XM_011533346 XP_011531648 XM_011533347 XP_011531649 NM_144633 NP_653234 |
Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Primarily expressed in the nervous system. {ECO:0000269|PubMed:12890647}. |
KCNH8 CRISPR/Cas9 KO Plasmid (h) - sc-414376 from Santa Cruz Biotechnology
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KCNH8 HDR Plasmid (h) - sc-414376-HDR from Santa Cruz Biotechnology
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KCNH8 Double Nickase Plasmid (h) - sc-414376-NIC from Santa Cruz Biotechnology
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KCNH8 Double Nickase Plasmid (h2) - sc-414376-NIC-2 from Santa Cruz Biotechnology
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KCNH8 CRISPR Activation Plasmid (h) - sc-414376-ACT from Santa Cruz Biotechnology
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KCNH8 CRISPR Activation Plasmid (h2) - sc-414376-ACT-2 from Santa Cruz Biotechnology
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KCNH8 Lentiviral Activation Particles (h) - sc-414376-LAC from Santa Cruz Biotechnology
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KCNH8 Lentiviral Activation Particles (h2) - sc-414376-LAC-2 from Santa Cruz Biotechnology
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KCNH8 siRNA (h) - sc-78288 from Santa Cruz Biotechnology
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KCNH8 shRNA Plasmid (h) - sc-78288-SH from Santa Cruz Biotechnology
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KCNH8 shRNA (h) Lentiviral Particles - sc-78288-V from Santa Cruz Biotechnology
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Kv12.1 RNAi - H00131096-R03 from Novus Biologicals
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MISSION® esiRNA - EHU016311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10948 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10948 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09778 from Sigma-Aldrich
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KCNH8 siRNA (Human) - CRJ5055 from Cohesion Biosciences
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KCNH8, siRNA - MBS8234758 from MyBioSource
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KCNH8, siRNA - MBS8229418 from MyBioSource
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KCNH8, siRNA - MBS8236616 from MyBioSource
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shRNA set against Human KCNH8 (NM_144633.2) - SHH323119 from Creative biogene
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shRNA set against Human KCNH8(NM_144633.2) - SHH137927 from Creative biogene
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KCNH8 shRNA Plasmid (Human) - CHJ5055 from Cohesion Biosciences
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KCNH8 miRNA 3'UTR clone - MiUTR1H-05115 from Creative biogene
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