| Gene Symbol | Apoa1 |
|---|---|
| Entrez Gene | 11806 |
| Alt Symbol | Alp-1, Apoa-1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2, Sep2, apo-AI, apoA-I |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | apolipoprotein A-I |
| Other Description | apolipoprotein A1 |
| Swissprots | O09042 O08855 Q00623 Q8BPD5 |
| Accessions | AAB58424 AAB58425 AAB58426 AAB58427 CAA45561 EDL25677 EDL25678 EDL25679 EDL25680 Q00623 AK076187 BAC36241 AK131864 BAE20837 AK149576 BAE28968 AK161536 BAE36448 BC012253 AAH12253 BC019837 AAH19837 BC091745 AAH91745 BU755007 L04151 S80442 AAB35539 X64262 CAA45560 NM_009692 NP_033822 |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Major protein of plasma HDL, also found in chylomicrons. |
| Top Pathways | PPAR signaling pathway, African trypanosomiasis, Fat digestion and absorption, Vitamin digestion and absorption |