Gene Symbol | CCDC101 |
---|---|
Entrez Gene | 112869 |
Alt Symbol | SGF29, STAF36 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 101 |
Other Description | SAGA-associated factor 29 homolog|coiled-coil domain-containing protein 101 |
Swissprots | Q96ES7 Q96MF5 |
Accessions | EAW52272 Q96ES7 AA132314 AA132818 AK057008 BAB71340 BC011981 AAH11981 NM_138414 NP_612423 |
Function | Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA- type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. {ECO:0000269|PubMed:19103755}. |
Subcellular Location | Nucleus {ECO:0000250}. |