Gene Symbol | HSP90B1 |
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Entrez Gene | 7184 |
Alt Symbol | ECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock protein 90kDa beta (Grp94), member 1 |
Other Description | 94 kDa glucose-regulated protein|endoplasmin|endothelial cell (HBMEC) glycoprotein|epididymis luminal protein 35|epididymis secretory sperm binding protein Li 125m|heat shock protein 90 kDa beta member 1|stress-inducible tumor rejection antigen gp96|tumor rejection antigen (gp96) 1|tumor rejection antigen 1 |
Swissprots | P14625 Q96A97 |
Accessions | AAA58621 AAA68201 CAK18765 EAW97723 EAW97724 P14625 AB209534 BAD92771 AF087988 AJ890084 CAI64497 AK025459 AK025862 AK295262 BAG58251 AK298996 BAG61085 AK300521 BAG62233 AY040226 AAK74072 BC009195 AAH09195 BC066656 AAH66656 CA419931 EU794608 ACJ13662 FJ460515 ACS44652 S74942 AAD14161 X15187 CAA33261 NM_003299 NP_003290 |
Function | Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. {ECO:0000250, ECO:0000269|PubMed:18264092}. |
Subcellular Location | Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Prostate cancer, NOD-like receptor signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway, Estrogen signaling pathway |
Dog GRP94 full length protein - ab92290 from Abcam
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Human GRP94 full length protein - ab188463 from Abcam
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Human GRP94 full length protein - ab87144 from Abcam
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Human GRP94 peptide - ab101303 from Abcam
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HSP90B1 / GP96 / GRP94 Antibody Blocking Peptide - LS-E1307 from LifeSpan Bioscience
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HSP90B1 / GP96 / GRP94 Antibody Blocking Peptide - LS-E14764 from LifeSpan Bioscience
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HSP90B1 / GP96 / GRP94 Antibody Blocking Peptide - LS-E14763 from LifeSpan Bioscience
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HSP90B1 / GP96 / GRP94 Antibody Blocking Peptide - LS-E7634 from LifeSpan Bioscience
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HSP90B1 / GP96 / GRP94 Antibody Blocking Peptide - LS-E26118 from LifeSpan Bioscience
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Recombinant Human gp96/HSP90B1/GRP94 Protein - H00007184-P01 from Novus Biologicals
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Recombinant Human gp96/HSP90B1/GRP94 Protein - H00007184-P02 from Novus Biologicals
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Recombinant Human gp96/HSP90B1/GRP94 Protein - NBC1-21058 from Novus Biologicals
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HSP90B1-Antibody-Center-Blocking-peptide - BP11926c from Abgent, a WuXi AppTec company
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HSP90B1-Antibody-N-term-Blocking-Peptide - BP4899a from Abgent, a WuXi AppTec company
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GPR94/TRA1 blocking peptide - GTX89299-PEP from GeneTex
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Recombinant human Endoplasmin (OPCA00893) - OPCA00893 from Aviva Systems Biology
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HSP90B1 Protein (OPPA01850) - OPPA01850 from Aviva Systems Biology
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Human HSP90B1 protein - orb245483 from Biorbyt
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Human HSP90B1 protein - orb81516 from Biorbyt
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HSP90B1 Blocking Peptide - 33R-1658 from Fitzgerald
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HSP90B1 Blocking Peptide - 33R-2350 from Fitzgerald
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HSP90B1 protein (His tag) - 80R-3456 from Fitzgerald
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HSP90B1 protein (His tag) - 80R-1121 from Fitzgerald
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GRP94 Blocking Peptide - abx063389 from Abbexa
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Human HSP90b1 Protein - abx067019 from Abbexa
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