| Gene Symbol | FTCD |
|---|---|
| Entrez Gene | 10841 |
| Alt Symbol | LCHC1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | formimidoyltransferase cyclodeaminase |
| Other Description | formimidoyltransferase-cyclodeaminase|formiminotransferase cyclodeaminase|formiminotransferase-cyclodeaminase |
| Swissprots | Q86V03 Q9HCT5 B9EGD0 Q9HCT6 Q9HCT4 O95954 Q9UHJ2 |
| Accessions | EAX09308 EAX09309 EAX09310 EAX09311 EAX09312 EAX09313 EAX09314 EAX09315 O95954 AA719282 AF169017 AAF15558 AF289021 AAG01852 AF289022 AAG01853 AF289023 AAG01854 AF289024 AAG01855 AL109817 BC032037 AAH32037 BC052248 AAH52248 BC136383 AAI36384 BC136395 AAI36396 BI966164 BM021970 U91541 AAD15627 XM_006723961 XP_006724024 XM_006723962 XP_006724025 XM_011529434 XP_011527736 XM_011529435 XP_011527737 XM_011529436 XP_011527738 XM_011529437 XP_011527739 XM_011529438 XP_011527740 XM_011529439 XP_011527741 XM_011529440 XP_011527742 XR_937433 NM_006657 NP_006648 NM_206965 NP_996848 |
| Function | Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. |
| Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:16534631}. Golgi apparatus {ECO:0000250}. Note=More abundantly located around the mother centriole. |
| Top Pathways | Histidine metabolism, One carbon pool by folate |