| Gene Symbol | HESX1 |
|---|---|
| Entrez Gene | 8820 |
| Alt Symbol | ANF, CPHD5, RPX |
| Species | Human |
| Gene Type | protein-coding |
| Description | HESX homeobox 1 |
| Other Description | Rathke pouch homeobox|hAnf|homeobox expressed in ES cells 1|homeobox protein ANF |
| Swissprots | Q9UBX0 Q52LC5 Q99667 |
| Accessions | AAB39561 AAC24523 EAW65333 EAW65334 Q9UBX0 AI652412 BC069515 AAH69515 BC093979 AAH93979 BC112089 AAI12090 EU446670 ABZ92199 XM_005265526 XP_005265583 XM_006713379 XP_006713442 XM_011534204 XP_011532506 XM_011534205 XP_011532507 NM_003865 NP_003856 |
| Function | Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Top Pathways | Signaling pathways regulating pluripotency of stem cells |
HESX homeobox 1, ELISA Kit - MBS9327169 from MyBioSource
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Human HESX1 ELISA Kit - E018484 from Biobool
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