| Gene Symbol | LEU2 |
|---|---|
| Entrez Gene | 850342 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | 3-isopropylmalate dehydrogenase |
| Other Description | - |
| Swissprots | D6VQZ6 P04173 |
| Accessions | DAA07465 P04173 NM_001178665 NP_009911 |
| Function | Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, C5-Branched dibasic acid metabolism |