| Gene Symbol |
IQSEC3
|
| Entrez Gene |
440073
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
IQ motif and Sec7 domain 3
|
| Other Description |
IQ motif and SEC7 domain-containing protein 3
|
| Swissprots |
Q8TB43 A6NKV9 A6NIF2 Q9UPP2
|
| Accessions |
EAW88980 EAW88981 EAW88982 EAW88983 EAW88984 Q9UPP2 AB029033 BAA83062 AK091953 BC024764 AAH24764 BC042067 XM_011520957 XP_011519259 XM_011520958 XP_011519260 XM_011520959 XP_011519261 XM_011520960 XP_011519262 XM_011520961 XP_011519263 XR_931511 XR_931512 XR_931513 NM_001170738 NP_001164209 NM_015232 NP_056047
|
| Function |
Acts as a guanine nucleotide exchange factor (GEF) for ARF1. {ECO:0000269|PubMed:17981261}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17981261}.
|
| Tissue Specificity |
Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells. {ECO:0000269|PubMed:17981261}.
|
| Top Pathways |
Endocytosis
|