GRIK2

Gene Symbol	GRIK2
Entrez Gene	2898
Alt Symbol	EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, kainate 2
Other Description	bA487F5.1|excitatory amino acid receptor 4|gluR-6|glutamate receptor 6|glutamate receptor form A|glutamate receptor form B|glutamate receptor form C|glutamate receptor form D|glutamate receptor form E|glutamate receptor ionotropic, kainate 2
Swissprots	D7RWZ4 Q13002 D7RWZ3 Q96KS8 Q8WWS1 Q96KS6 D7RWZ6 A6NMY9 Q96KS7 B5MCV0 D7RWZ7 D7RWZ5
Accessions	CAC25104 CCQ43905 EAW48446 EAW48447 EAW48448 Q13002 AI087397 AJ252246 CAC81020 AJ301608 CAC67485 AJ301609 CAC67486 AJ301610 CAC67487 AK023497 AK289542 BAF82231 AK291965 BAF84654 AK303721 BAH14032 AW949408 BC037954 AAH37954 BC063814 AAH63814 BM722353 BQ717946 HM149335 ADH93569 HM149336 ADH93570 HM149337 ADH93571 HM149338 ADH93572 HM149339 ADH93573 HM149340 ADH93574 JF432691 ADZ15908 S75105 U16126 AAC50420 XM_005266945 XP_005267002 XM_005266946 XP_005267003 XM_011535777 XP_011534079 XM_011535778 XP_011534080 XM_011535779 XP_011534081 XM_011535780 XP_011534082 XM_011535781 XP_011534083 NM_001166247 NP_001159719 NM_021956 NP_068775 NM_175768 NP_786944
Function	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expression is higher in cerebellum than in cerebral cortex.
Top Pathways	Glutamatergic synapse, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GRIK2-Over-expression-Lysate - LY12717a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

GRIK2 293 Cell Lysate - 405905 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

Glutamate Receptor 6 Overexpression Lysate (Native) - NBP2-06497 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

GRIK2 Over-expression Lysate Product - GWB-62CE40 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Glutamate Receptor 6 Overexpression Lysate (Native) - NBP2-05049 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Glutamate Receptor 6 Overexpression Lysate (Denatured) - H00002898-T03 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human GRIK2 Knockdown Stable Cell Line - CSC-DC006654 from Creative biogene Category Cell Line Species Human

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