GRIK2

Gene Symbol GRIK2
Entrez Gene 2898
Alt Symbol EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Species Human
Gene Type protein-coding
Description glutamate receptor, ionotropic, kainate 2
Other Description bA487F5.1|excitatory amino acid receptor 4|gluR-6|glutamate receptor 6|glutamate receptor form A|glutamate receptor form B|glutamate receptor form C|glutamate receptor form D|glutamate receptor form E|glutamate receptor ionotropic, kainate 2
Swissprots D7RWZ4 Q13002 D7RWZ3 Q96KS8 Q8WWS1 Q96KS6 D7RWZ6 A6NMY9 Q96KS7 B5MCV0 D7RWZ7 D7RWZ5
Accessions CAC25104 CCQ43905 EAW48446 EAW48447 EAW48448 Q13002 AI087397 AJ252246 CAC81020 AJ301608 CAC67485 AJ301609 CAC67486 AJ301610 CAC67487 AK023497 AK289542 BAF82231 AK291965 BAF84654 AK303721 BAH14032 AW949408 BC037954 AAH37954 BC063814 AAH63814 BM722353 BQ717946 HM149335 ADH93569 HM149336 ADH93570 HM149337 ADH93571 HM149338 ADH93572 HM149339 ADH93573 HM149340 ADH93574 JF432691 ADZ15908 S75105 U16126 AAC50420 XM_005266945 XP_005267002 XM_005266946 XP_005267003 XM_011535777 XP_011534079 XM_011535778 XP_011534080 XM_011535779 XP_011534081 XM_011535780 XP_011534082 XM_011535781 XP_011534083 NM_001166247 NP_001159719 NM_021956 NP_068775 NM_175768 NP_786944
Function Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Tissue Specificity Expression is higher in cerebellum than in cerebral cortex.
Top Pathways Glutamatergic synapse, Neuroactive ligand-receptor interaction

GluR-6 CRISPR/Cas9 KO Plasmid (h) - sc-402982 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 HDR Plasmid (h) - sc-402982-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 Double Nickase Plasmid (h) - sc-402982-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 Double Nickase Plasmid (h2) - sc-402982-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 CRISPR Activation Plasmid (h) - sc-402982-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 CRISPR Activation Plasmid (h2) - sc-402982-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 Lentiviral Activation Particles (h) - sc-402982-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 Lentiviral Activation Particles (h2) - sc-402982-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GluR-6 siRNA (h) - sc-37105 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GluR-6 shRNA Plasmid (h) - sc-37105-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GluR-6 shRNA (h) Lentiviral Particles - sc-37105-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU095631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU095061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9682 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9682 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04755 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04755

GRIK2 siRNA (Human) - CRH1952 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Glutamate Receptor 6 RNAi - H00002898-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GRIK2 - MBS8225593 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GRIK2 (NM_021956.4) - SHH307838 from Creative biogene

Category siRNA
Species Reactivities Human

GRIK2 shRNA Plasmid (Human) - CHH1952 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GRIK2 miRNA 3'UTR clone - MiUTR3H-00881 from Creative biogene

Species Reactivities Human

GRIK2 miRNA 3'UTR clone - MiUTR3H-00882 from Creative biogene

Species Reactivities Human

GRIK2 miRNA 3'UTR clone - MiUTR3H-00883 from Creative biogene

Species Reactivities Human
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