| Gene Symbol | FUT2 |
|---|---|
| Entrez Gene | 2524 |
| Alt Symbol | B12QTL1, SE, SEC2, Se2, sej |
| Species | Human |
| Gene Type | protein-coding |
| Description | fucosyltransferase 2 (secretor status included) |
| Other Description | GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2|alpha (1,2) fucosyltransferase|alpha(1,2)FT 2|alpha(1,2)FT2|galactoside 2-alpha-L-fucosyltransferase 2|secretor blood group alpha-2-fucosyltransferase|secretor factor |
| Swissprots | Q10981 Q0VAG5 Q14338 Q5D0G2 |
| Accessions | AAC24453 AAV65715 AAX14047 ABC59308 BAA13943 BAA13944 CAQ56301 CAQ68511 CAQ81978 CAQ81979 CAQ81980 CAQ81981 CAQ81982 CAQ81983 CAQ81984 CAQ81985 EAW52379 Q10981 AK290277 BAF82966 AY751739 AAU47383 BC001899 BC121066 BE266792 BT006657 AAP35303 D87942 BAA21684 DA918525 NM_000511 NP_000502 NM_001097638 NP_001091107 |
| Function | Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
| Tissue Specificity | Small intestine, colon and lung. |
| Top Pathways | Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |