Gene Symbol | LGALS3 |
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Entrez Gene | 3958 |
Alt Symbol | CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2 |
Species | Human |
Gene Type | protein-coding |
Description | lectin, galactoside-binding, soluble, 3 |
Other Description | 35 kDa lectin|IgE-binding protein|MAC-2 antigen|carbohydrate-binding protein 35|galactose-specific lectin 3|galectin-3|laminin-binding protein|lectin L-29 |
Swissprots | B2RC38 P17931 Q96J47 Q6IBA7 Q16005 |
Accessions | AAB86584 BAC45249 CBX53892 EAW80658 EAW80660 P17931 AB006780 BAA22164 AB209391 BAD92628 AF266280 AAG44701 AK314929 BAG37435 BC001120 AAH01120 BC053667 AAH53667 BC068068 AAH68068 BC128253 BC128403 BG332134 BQ645629 BU681070 BX161455 CAD61918 BX641090 CAE46042 CD518618 CR456897 CAG33178 CR542097 CAG46894 DQ892594 ABM83520 EU176706 ABW03507 M35368 AAA88086 M36682 AAA36163 M57710 AAA35607 M64303 S59012 AAB26229 XM_011536759 XP_011535061 NM_001177388 NP_001170859 NM_002306 NP_002297 NR_003225 |
Function | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}. |
Subcellular Location | Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface. |
Tissue Specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. {ECO:0000269|PubMed:19497882}. |
Galectin-3 Human SimpleStep ELISA™ Kit - ab188394 from Abcam
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Human LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F5913 from LifeSpan Bioscience
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Mouse LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F5943 from LifeSpan Bioscience
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Rat LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F5944 from LifeSpan Bioscience
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Human LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F2670 from LifeSpan Bioscience
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Mouse LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F2671 from LifeSpan Bioscience
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Human LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F442 from LifeSpan Bioscience
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Mouse/Human/Rat LGALS3 / Galectin 3 ELISA Kit (Cell-Based ELISA) - LS-F2009 from LifeSpan Bioscience
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Mouse LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F494 from LifeSpan Bioscience
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Human LGALS3 / Galectin 3 ELISA Kit (Sandwich ELISA) - LS-F702 from LifeSpan Bioscience
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Human LGALS3 / Galectin-3 ELISA Kit - RAB0661 from Sigma-Aldrich
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Galectin-3/LGALS3 BioAssay ELISA Kit, Human - 143846 from USBiological Life Science
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Galectin-3/LGALS3 BioAssay ELISA Kit, Mouse - 143847 from USBiological Life Science
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Human Galectin-3 Quantikine ELISA Kit - DGAL30 from R&D Systems
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Human Galectin-3 DuoSet ELISA - DY1154 from R&D Systems
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Mouse Galectin-3 DuoSet ELISA - DY1197 from R&D Systems
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Human Galectin-3 Quantikine SixPak (6 Plates) - SGAL30 from R&D Systems
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Human Galectin-3 Quantikine PharmPak (50 Plates) - PDGAL30 from R&D Systems
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Human Galectin3 ELISA kit - 55R-27755 from Fitzgerald
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Galectin-3 ELISA Kit (Human) : 96 Wells (OKAG00226) - OKAG00226 from Aviva Systems Biology
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Human Galectin-3 ELISA Kit - abx055001 from Abbexa
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Human Lgals3 ELISA Kit - abx054380 from Abbexa
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Galectin 3, GAL3, Human, ELISA Kit - E-EL-H1470 from ARP American Research Products
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Galectin 2 (GAL2), Human, ELISA Kit - SEA302Hu from ARP American Research Products
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Galectin 3 (GAL3), Human, ELISA Kit - SEA303Hu from ARP American Research Products
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