LGALS3

Gene Symbol	LGALS3
Entrez Gene	3958
Alt Symbol	CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
Species	Human
Gene Type	protein-coding
Description	lectin, galactoside-binding, soluble, 3
Other Description	35 kDa lectin|IgE-binding protein|MAC-2 antigen|carbohydrate-binding protein 35|galactose-specific lectin 3|galectin-3|laminin-binding protein|lectin L-29
Swissprots	B2RC38 P17931 Q96J47 Q6IBA7 Q16005
Accessions	AAB86584 BAC45249 CBX53892 EAW80658 EAW80660 P17931 AB006780 BAA22164 AB209391 BAD92628 AF266280 AAG44701 AK314929 BAG37435 BC001120 AAH01120 BC053667 AAH53667 BC068068 AAH68068 BC128253 BC128403 BG332134 BQ645629 BU681070 BX161455 CAD61918 BX641090 CAE46042 CD518618 CR456897 CAG33178 CR542097 CAG46894 DQ892594 ABM83520 EU176706 ABW03507 M35368 AAA88086 M36682 AAA36163 M57710 AAA35607 M64303 S59012 AAB26229 XM_011536759 XP_011535061 NM_001177388 NP_001170859 NM_002306 NP_002297 NR_003225
Function	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
Subcellular Location	Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
Tissue Specificity	A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. {ECO:0000269|PubMed:19497882}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LGALS3-Over-expression-Lysate - LY12848a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

LGALS3-Over-expression-Lysate - LY12817a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

Galectin-3 Lysate(Denatured) - H00003958-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

LGALS3 293 Cell Lysate - 400795 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Galectin-3 Overexpression Lysate (Denatured) - H00003958-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Galectin-3 Overexpression Lysate (Native) - NBL1-12501 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

galectin-3 (h): 293T Lysate - sc-116566 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

galectin-3 (h2): 293T Lysate - sc-176286 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

LGALS3 Over-expression Lysate Product - GWB-4D4920 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Galectin-3 (with HisTag) - orb179979 from Biorbyt Prices $774.00 Sizes 1 mg Disease Cancer

LGALS3-knockout Cell lysate - LC810128 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human LGALS3 Knockdown Stable Cell Line - CSC-DC008658 from Creative biogene Category Cell Line Species Human

Human LGALS3 Knockout Cell Line-HeLa - CSC-RT0503 from Creative biogene Category Cell Line Species Human

LGALS3 KO Cell Lysate-HeLa - CLKO-0008 from Creative biogene Category Cell Lysate

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