| Gene Symbol | Rtca |
|---|---|
| Entrez Gene | 66368 |
| Alt Symbol | 2310009A18Rik, AI450277, RPC, Rtcd1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | RNA 3'-terminal phosphate cyclase |
| Other Description | RNA cyclase|RNA terminal phosphate cyclase domain 1|RNA terminal phosphate cyclase domain-containing protein 1|RNA-3'-phosphate cyclase |
| Swissprots | Q3TVV2 Q9D7H3 |
| Accessions | EDL12383 EDL12384 Q9D7H3 AK002543 AK009245 BAB26164 AK151108 BAE30118 AK151400 BAE30368 AK152129 BAE30970 AK159961 BAE35516 AK167830 BAE39852 AK177950 AK179135 AK186063 AK190960 AK193515 AK207601 AK209245 AK212568 AK215360 AK219075 BC016519 AAH16519 BC042473 BC051062 BC090403 AAH90403 BM899781 XM_006501883 XP_006501946 XM_006501884 XP_006501947 NM_025517 NP_079793 |
| Function | Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus, nucleoplasm {ECO:0000250}. |