DEDD

Gene Symbol	DEDD
Entrez Gene	9191
Alt Symbol	CASP8IP1, DEDD1, DEFT, FLDED1, KE05
Species	Human
Gene Type	protein-coding
Description	death effector domain containing
Other Description	DEDPro1|FLDED-1|death effector domain-containing protein|death effector domain-containing testicular molecule
Swissprots	O60737 D3DVF5 O75618
Accessions	EAW52648 EAW52649 EAW52650 EAW52651 EAW52652 EAW52653 O75618 AF043733 AAC80280 AF064605 AAC17110 AF083236 AAC33105 AF100341 AAD16414 AJ010973 CAA09445 AK001497 AK022531 BAG51086 AK296629 BAG59233 BC013910 AAH13910 BC016724 AAH16724 BG565440 CR536556 CAG38793 JF432647 ADZ15864 XM_005245597 XP_005245654 XM_005245598 XP_005245655 XM_005245599 XP_005245656 XM_005245600 XP_005245657 NM_001039711 NP_001034800 NM_001039712 NP_001034801 NM_032998 NP_127491 NM_004216
Function	A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Nucleus, nucleolus {ECO:0000250}. Note=Translocated to the nucleus during CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18 intermediate filament network in simple epithelial cells. {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in testis. {ECO:0000269|PubMed:9832420}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DEDD (G-6) - sc-271191 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

DEDD (C-18) - sc-27051 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

DEDD (G-17) - sc-27052 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

DEDD (H-4) - sc-271192 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

DEDD (N-20) - sc-27050 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-DEDD antibody - ab203655 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DEDD antibody - ab192534 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DEDD antibody - ab201173 from Abcam Prices $359.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD antibody - ab56480 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-DEDD antibody - N-terminal - ab157148 from Abcam Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191, AP) - LS-C208783 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191, APC) - LS-C208784 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191, Biotin) - LS-C208785 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191, FITC) - LS-C208786 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa129-223) - LS-C186235 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191, Azide-free, HRP) - LS-C208787 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa114-141) - LS-C320798 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa91-191) - LS-C307212 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-DEDD Antibody (aa165-191, PE) - LS-C208788 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody - LS-C341879 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (Internal) - LS-C345657 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DEDD Antibody (aa165-191) - LS-C159450 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

DEDD Antibody - NBP1-31686 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

DEDD Antibody - H00009191-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

DEDD Antibody (1C7) - H00009191-M01 from Novus Biologicals Host Mouse Clonality Monoclonal Clone 1C7

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