| Gene Symbol | FUT8 |
|---|---|
| Entrez Gene | 2530 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| Other Description | GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase|GDP-fucose--glycoprotein fucosyltransferase|alpha-(1,6)-fucosyltransferase|alpha1-6FucT|glycoprotein 6-alpha-L-fucosyltransferase |
| Swissprots | Q8IUA5 Q9BYC6 B4DFS7 G3V5N0 O00235 Q9P2U5 Q9BYC5 Q9P2U6 |
| Accessions | BAA92858 BAA92859 BAB40975 CAD79985 CAV31713 CAZ91290 EAW80911 EAW80912 EAW80913 EAW80914 EAW80915 EAW80916 EAW80917 Q9BYC5 AB049740 BAB40929 AF052088 AJ514324 CAD55804 AJ514325 CAD55805 AJ536053 CAD59924 AJ536054 CAD59925 AJ536055 CAD59926 AJ536056 CAD59927 AJ539535 CAD62444 AJ539536 CAD62445 AK292413 BAF85102 AK294242 BAG57538 BC025385 BC093889 AAH93889 BC101816 AAI01817 BC142958 AAI42959 BQ962258 BX107537 D89289 BAA19764 DB089189 Y17976 CAA76985 Y17977 CAA76986 Y17978 CAA76987 Y17979 CAA76988 XM_011536613 XP_011534915 XM_011536614 XP_011534916 NM_004480 NP_004471 NM_178155 NP_835368 NM_178156 NP_835369 NR_038167 NR_038170 NM_178154 NM_178157 |
| Function | Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. {ECO:0000269|PubMed:17172260, ECO:0000269|PubMed:9133635}. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}. |
| Top Pathways | N-Glycan biosynthesis, Glycosaminoglycan biosynthesis - keratan sulfate, Transcriptional misregulation in cancer |