Gene Symbol | sim |
---|---|
Entrez Gene | 41612 |
Alt Symbol | 0483/09, 0716/08, 0899/14, 0953/08, 1002/10, 1034/02, 1050/13, 1110/04, 1111/10, 1330/08, 1479/04, CG7771, Dmel\CG7771, S8, SIM, Sim, bHLHe16, l(3)87Ea, l(3)E320, l(3)RD, l(3)S8, l(3)s8, schm, shm |
Species | Drosophila |
Gene Type | protein-coding |
Description | single-minded |
Other Description | CG7771-PA|CG7771-PB|CG7771-PC|CG7771-PD|Single-minded|Singled-minded|schmal|sim-PA|sim-PB|sim-PC|sim-PD|single minded|singleminded |
Swissprots | Q8MQI7 P05709 Q7KSL7 Q9VFZ3 O96521 |
Accessions | AAF54902 AAN14343 AGB95909 AGB95910 AY129457 AAM76199 NM_001275598 NP_001262527 NM_001275599 NP_001262528 NM_079616 NP_524340 NM_169495 NP_731771 |
Function | Transcription factor that functions as a master developmental regulator controlling midline development of the ventral nerve cord. Required to correctly specify the formation of the central brain complex, which controls walking behavior. Also required for correct patterning of the embryonic genital disk and anal pad anlage. Plays a role in synapse development. {ECO:0000269|PubMed:12221007, ECO:0000269|PubMed:23644463, ECO:0000269|PubMed:9840810}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Tissue Specificity | Embryonic nerve cord. {ECO:0000269|PubMed:12221007}. |