| Gene Symbol |
Gad2
|
| Entrez Gene |
24380
|
| Alt Symbol |
gad65
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
glutamate decarboxylase 2
|
| Other Description |
65 kDa glutamic acid decarboxylase|GAD-65|Glutamate decarboxylase 2 (islet)|glutamate decarboxylase 65 kDa isoform|glutamic acid decarboxylase 2|glutamic acid decarboxylase 65
|
| Swissprots |
Q05683
|
| Accessions |
AAC64947 EDL83940 EDL83941 Q05683 M72422 AAA63488 NM_012563 NP_036695
|
| Function |
Catalyzes the production of GABA.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}.
|
| Top Pathways |
Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism
|