| Gene Symbol | Gad2 |
|---|---|
| Entrez Gene | 24380 |
| Alt Symbol | gad65 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | glutamate decarboxylase 2 |
| Other Description | 65 kDa glutamic acid decarboxylase|GAD-65|Glutamate decarboxylase 2 (islet)|glutamate decarboxylase 65 kDa isoform|glutamic acid decarboxylase 2|glutamic acid decarboxylase 65 |
| Swissprots | Q05683 |
| Accessions | AAC64947 EDL83940 EDL83941 Q05683 M72422 AAA63488 NM_012563 NP_036695 |
| Function | Catalyzes the production of GABA. |
| Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}. |
| Top Pathways | Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism |
GAD-65 siRNA (r) - sc-61888 from Santa Cruz Biotechnology
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GAD-65 shRNA Plasmid (r) - sc-61888-SH from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN54263 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND54263 from Sigma-Aldrich
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GAD2 siRNA (Rat) - CRR0112 from Cohesion Biosciences
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GAD2 - MBS8219222 from MyBioSource
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shRNA set against Rat GAD2 (NM_012563.1) - SHH298685 from Creative biogene
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shRNA set against Rat Gad2(NM_012563.1) - SHH074945 from Creative biogene
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Rat GAD2 siRNA - orb294961 from Biorbyt
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GAD2 shRNA Plasmid (Rat) - CHR0112 from Cohesion Biosciences
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GAD2 miRNA 3'UTR clone - MiUTR1R-02022 from Creative biogene
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