Gene Symbol | GAPT |
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Entrez Gene | 202309 |
Alt Symbol | C5orf29 |
Species | Human |
Gene Type | protein-coding |
Description | GRB2-binding adaptor protein, transmembrane |
Other Description | GRB2-binding transmembrane adaptor|growth factor receptor-bound protein 2-binding adapter protein, transmembrane|protein GAPT |
Swissprots | Q8N292 |
Accessions | CAC38692 CAD48812 EAW54974 EAW54975 Q8N292 AA220230 AK090960 BAC03557 BC063534 AAH63534 DA008727 DA347824 NM_001304428 NP_001291357 NM_001304429 NP_001291358 NM_001304431 NP_001291360 NM_152687 NP_689900 |
Function | Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18559951}; Single-pass membrane protein {ECO:0000269|PubMed:18559951}. |
Tissue Specificity | Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells. {ECO:0000269|PubMed:18559951}. |
GAPT (B-6) - sc-398293 from Santa Cruz Biotechnology
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GAPT (C-12) - sc-133363 from Santa Cruz Biotechnology
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GAPT (G-13) - sc-133364 from Santa Cruz Biotechnology
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GAPT (H-8) - sc-398271 from Santa Cruz Biotechnology
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GAPT (H-52) - sc-382456 from Santa Cruz Biotechnology
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GAPT (T-13) - sc-133365 from Santa Cruz Biotechnology
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Anti-GAPT antibody - ab156083 from Abcam
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Anti-GAPT Antibody (aa84-112, APC) - LS-C257551 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112, Biotin) - LS-C257552 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112, AP) - LS-C257549 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112, Azide-free, HRP) - LS-C257554 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112, FITC) - LS-C257553 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112, PE) - LS-C257555 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112) - LS-C157762 from LifeSpan Bioscience
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Anti-GAPT Antibody (aa84-112) - LS-C321550 from LifeSpan Bioscience
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GAPT Antibody - NBP1-86773 from Novus Biologicals
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GAPT Polyclonal Antibody - bs-13284R from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13284R-A350 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13284R-A488 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13284R-A555 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13284R-A647 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, Cy3 Conjugated - bs-13284R-Cy3 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, Cy5 Conjugated - bs-13284R-Cy5 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, Cy5.5 Conjugated - bs-13284R-Cy5.5 from Bioss
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Rabbit Anti-GAPT Polyclonal Antibody, Cy7 Conjugated - bs-13284R-Cy7 from Bioss
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