ST14

Gene Symbol ST14
Entrez Gene 6768
Alt Symbol ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14
Species Human
Gene Type protein-coding
Description suppression of tumorigenicity 14 (colon carcinoma)
Other Description membrane-type serine protease 1|prostamin|serine protease 14|serine protease TADG-15|suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)|suppressor of tumorigenicity 14 protein|tumor associated differentially expressed gene 15 protein|tumor-associated differentially-expressed gene 15 protein
Swissprots Q9HCA3 Q9BS01 Q9Y5Y6 Q9HB36 Q9H3S0
Accessions AAG13949 EAW67776 Q9Y5Y6 AB030036 BAB20376 AF057145 AAG15395 AF118224 AAD42765 AF133086 AAF00109 AK302454 BAG63749 AK314173 BAG36856 BC005826 AAH05826 BC018146 AAH18146 BC030532 AAH30532 BM791311 BQ059215 DQ891626 ABM82552 DQ894442 ABM85368 NM_021978 NP_068813
Function Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. {ECO:0000269|PubMed:18843291}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Top Pathways MicroRNAs in cancer

Human ST14 ORF Clone(NM_021978.3) - CDCR307331 from Creative Biomart

Species Human
Accession NM_021978.3

Human ST14 ORF Clone(NM_021978.3) - CDCR307332 from Creative Biomart

Species Human
Accession NM_021978.3

Human ST14 ORF Clone(NM_021978.3) - CDCL177142 from Creative Biomart

Species Human
Accession NM_021978.3

human ST14 ORF clone - CDCH086316 from Creative Biomart

Species Human
Accession NM_021978

human ST14 ORF clone - CDCH086317 from Creative Biomart

Species Human
Accession NM_021978

Human Matriptase ORF clone(NM_021978.3) - CDCL185282 from Creative biogene

Species Human

Human ST14 ORF Clone (BC030532) - CDCS415401 from Creative biogene

Species Human
Accession Q9Y5Y6

Human ST14 cDNA Clone(NM_021978.3) - CDFG003501 from Creative biogene

Species Human
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