ST14

Gene Symbol ST14
Entrez Gene 6768
Alt Symbol ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14
Species Human
Gene Type protein-coding
Description suppression of tumorigenicity 14 (colon carcinoma)
Other Description membrane-type serine protease 1|prostamin|serine protease 14|serine protease TADG-15|suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)|suppressor of tumorigenicity 14 protein|tumor associated differentially expressed gene 15 protein|tumor-associated differentially-expressed gene 15 protein
Swissprots Q9HCA3 Q9BS01 Q9Y5Y6 Q9HB36 Q9H3S0
Accessions AAG13949 EAW67776 Q9Y5Y6 AB030036 BAB20376 AF057145 AAG15395 AF118224 AAD42765 AF133086 AAF00109 AK302454 BAG63749 AK314173 BAG36856 BC005826 AAH05826 BC018146 AAH18146 BC030532 AAH30532 BM791311 BQ059215 DQ891626 ABM82552 DQ894442 ABM85368 NM_021978 NP_068813
Function Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. {ECO:0000269|PubMed:18843291}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Top Pathways MicroRNAs in cancer

Matriptase CRISPR/Cas9 KO Plasmid (h) - sc-402971 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase HDR Plasmid (h) - sc-402971-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase Double Nickase Plasmid (h) - sc-402971-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase Double Nickase Plasmid (h2) - sc-402971-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase CRISPR Activation Plasmid (h) - sc-402971-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase CRISPR Activation Plasmid (h2) - sc-402971-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase Lentiviral Activation Particles (h) - sc-402971-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase Lentiviral Activation Particles (h2) - sc-402971-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase siRNA (h) - sc-43911 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Matriptase shRNA Plasmid (h) - sc-43911-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Matriptase shRNA (h) Lentiviral Particles - sc-43911-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU012511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2484 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2484 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04041 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04041

ST14 siRNA (Human) - CRH4626 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Matriptase/ST14 RNAi - H00006768-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ST14 - MBS8236891 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ST14 (NM_021978.3) - SHH418756 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ST14(NM_021978.3) - SHL037820 from Creative biogene

Category siRNA
Species Reactivities Human

Human ST14 siRNA - orb265128 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ST14 shRNA Plasmid (Human) - CHH4626 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ST14 miRNA 3'UTR clone - MiUTR1H-09944 from Creative biogene

Species Reactivities Human
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