Gene Symbol | DCTPP1 |
---|---|
Entrez Gene | 79077 |
Alt Symbol | CDA03, RS21C6, XTP3TPA |
Species | Human |
Gene Type | protein-coding |
Description | dCTP pyrophosphatase 1 |
Other Description | XTP3-transactivated gene A protein|XTP3-transactivated protein A|dCTPase 1|deoxycytidine-triphosphatase 1 |
Swissprots | Q9H773 |
Accessions | EAW52247 Q9H773 AF210430 AAK48422 AF212242 AAK14927 AK024843 BAB15025 AY453409 AAR26724 BC001344 AAH01344 CR457335 CAG33616 NM_024096 NP_077001 |
Function | Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non- canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | Pyrimidine metabolism |
Human XTP3TPA full length protein - ab119438 from Abcam
|
||||||||||
DCTPP1 / XTP3TPA Antibody Blocking Peptide - LS-E7125 from LifeSpan Bioscience
|
||||||||||
DCTPP1 / XTP3TPA Antibody Blocking Peptide - LS-E16893 from LifeSpan Bioscience
|
||||||||||
XTP3TPA Recombinant Protein - H00079077-P01 from Novus Biologicals
|
||||||||||
Recombinant Human XTP3TPA Protein - NBP1-78880 from Novus Biologicals
|
||||||||||
XTP3TPA-Antibody-N-term-Blocking-Peptide - BP2821a from Abgent, a WuXi AppTec company
|
||||||||||
Human DCTPP1 protein - orb168198 from Biorbyt
|
||||||||||
Human DCTPP1 protein (His Tag) - orb138685 from Biorbyt
|
||||||||||
DCTPP1 protein (His tag) - 80R-2123 from Fitzgerald
|
||||||||||
XTP3TPA Blocking Peptide - 33R-6521 from Fitzgerald
|
||||||||||
XTP3TPA Blocking Peptide - 33R-4552 from Fitzgerald
|
||||||||||
XTP3TPA / DCTPP1 (1-170, His-tag) - AR50206PU-N from Acris Antibodies
|
||||||||||
XTP3TPA / DCTPP1 (1-170, His-tag) - AR50206PU-S from Acris Antibodies
|
||||||||||
XTP3TPA / DCTPP1 - H00079077-P01-10 from Acris Antibodies
|
||||||||||
XTP3TPA / DCTPP1 - H00079077-P01-25 from Acris Antibodies
|
||||||||||
dCTP Pyrophosphatase 1, Human Recombinant - 228-12385-1 from RayBiotech
|
||||||||||
Recombinant Human dCTP Pyrophosphatase 1 - 228-12385-2 from RayBiotech
|
||||||||||
Recombinant Human dCTP Pyrophosphatase 1 - 228-12385-3 from RayBiotech
|
||||||||||
DCTPP1, 1-170aa, Human, His tag, E.coli - 01-P1381 from ARP American Research Products
|
||||||||||
DCTPP1 fusion protein - Ag10015 from Proteintech Group
|
||||||||||
DCTPP1 Human - ENPS-241 from NeoScientific
|
||||||||||
Recombinant Human DCUN1D1 Protein - BP001736-C271 from Syd Labs
|
||||||||||
DCTPP1, 1-170aa, Recombinant Protein - GWB-P0657G from Genway Biotech
|
||||||||||
Recombinant Human DCTPP1, GST-tagged - DCTPP1-11870H from Creative Biomart
|
||||||||||
Recombinant Human DCTPP1, His tagged - DCTPP1-445H from Creative Biomart
|