PAD3

Gene Symbol PAD3
Entrez Gene 822298
Alt Symbol CYP71B15, PHYTOALEXIN DEFICIENT 3
Species Arabidopsis thaliana
Gene Type protein-coding
Description protein PHYTOALEXIN DEFICIENT 3
Other Description -
Swissprots Q541X4 Q9LW27
Accessions AEE77220 BAB01230 Q9LW27 AK117967 BAC42604 NM_113595 NP_189318
Function Multifunctional enzyme involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes two reactions, the formation of dihydrocamalexate from indole-3-acetonitrile- cysteine conjugate and the oxidative decarboxylation of dihydrocamalexate which is the final step in camalexin biosynthesis. Required for the resistance to the fungal pathogens A.brassicicola, B.cinerea, B.elliptica, B.tulipae, L.maculans and Colletotrichum higginsianum. Seems not to be required for resistance to P.syringae, P.porri, and not involved in age-related resistance. {ECO:0000269|PubMed:10476063, ECO:0000269|PubMed:10590168, ECO:0000269|PubMed:11722772, ECO:0000269|PubMed:11884688, ECO:0000269|PubMed:12848825, ECO:0000269|PubMed:14675428, ECO:0000269|PubMed:16766671, ECO:0000269|PubMed:17384165, ECO:0000269|PubMed:17573535, ECO:0000269|PubMed:18567828, ECO:0000269|PubMed:19154205, ECO:0000269|PubMed:19567706, ECO:0000269|PubMed:20507477, ECO:0000269|PubMed:8090752}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Top Pathways Stilbenoid, diarylheptanoid and gingerol biosynthesis, Limonene and pinene degradation