Gene Symbol |
Tacr2
|
Entrez Gene |
25007
|
Alt Symbol |
Tac2r
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
tachykinin receptor 2
|
Other Description |
NK-2 receptor|NK-2R|SKR|Tachykinin 2 (substance K) receptor|neurokinin A receptor|substance-K receptor
|
Swissprots |
P16610
|
Accessions |
EDL92991 P16610 M31838 AAA42150 NM_080768 NP_542946
|
Function |
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|