FAP7

Gene Symbol FAP7
Entrez Gene 851388
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description Fap7p
Other Description -
Swissprots Q12055 D6VRI5 E9P8W4
Accessions DAA11695 Q12055 NM_001180226 NP_010115
Function Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity (By similarity). Involved in 18S rRNA maturation. Required for cleavage of the 20S pre-rRNA at site D in the cytoplasm. Involved in oxidative stress response. Required for POS9-dependent target gene transcription upon oxidative stress. {ECO:0000255|HAMAP-Rule:MF_03173, ECO:0000269|PubMed:10692169, ECO:0000269|PubMed:12837249, ECO:0000269|PubMed:16287850}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Ribosome biogenesis in eukaryotes, Purine metabolism

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