uspl1

Gene Symbol uspl1
Entrez Gene 445403
Alt Symbol c13orf22l
Species Zebrafish
Gene Type protein-coding
Description ubiquitin specific peptidase like 1
Other Description SUMO-specific isopeptidase USPL1|c13orf22 homolog, like|ubiquitin-specific peptidase-like protein 1
Swissprots A8WFQ9 Q6DRC5 B0JZK5
Accessions Q6DRC5 AY648834 AAT68152 BC154415 AAI54416 BC159218 AAI59219 BC162319 AAI62319 NM_001003880 NP_001003880
Function SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms. May have non-catalytic functions in Cajal bodies organization and cell proliferation. {ECO:0000269|PubMed:22878415}.
Subcellular Location Nucleus, Cajal body {ECO:0000269|PubMed:22878415}.

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