Gene Symbol |
uspl1
|
Entrez Gene |
445403
|
Alt Symbol |
c13orf22l
|
Species |
Zebrafish
|
Gene Type |
protein-coding
|
Description |
ubiquitin specific peptidase like 1
|
Other Description |
SUMO-specific isopeptidase USPL1|c13orf22 homolog, like|ubiquitin-specific peptidase-like protein 1
|
Swissprots |
A8WFQ9 Q6DRC5 B0JZK5
|
Accessions |
Q6DRC5 AY648834 AAT68152 BC154415 AAI54416 BC159218 AAI59219 BC162319 AAI62319 NM_001003880 NP_001003880
|
Function |
SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms. May have non-catalytic functions in Cajal bodies organization and cell proliferation. {ECO:0000269|PubMed:22878415}.
|
Subcellular Location |
Nucleus, Cajal body {ECO:0000269|PubMed:22878415}.
|