| Gene Symbol | PFKL |
|---|---|
| Entrez Gene | 5211 |
| Alt Symbol | ATP-PFK, PFK-B, PFK-L |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphofructokinase, liver |
| Other Description | 6-phosphofructokinase type B|6-phosphofructokinase, liver type|ATP-PFK|ATP-dependent 6-phosphofructokinase, liver type|liver-type 1-phosphofructokinase|phosphofructo-1-kinase isozyme B|phosphohexokinase |
| Swissprots | Q96IH4 P17858 Q9BR91 Q96A64 |
| Accessions | BAA95561 CAB46744 EAX09439 EAX09440 P17858 AB209127 BAD92364 AF086180 AK054735 BAG51419 AK091488 AK098228 AK303605 BAG64620 AK308437 BC004920 AAH04920 BC006422 AAH06422 BC007536 AAH07536 BC008964 AAH08964 BC009919 AAH09919 BC018295 AAH18295 BG390460 BQ067366 BU177678 BX351711 BX537446 CAD97688 BX641051 CAE46026 CA449348 CB997055 DQ893435 ABM84361 DQ896792 ABM87791 HY111158 X15573 CAA33597 XM_005261135 XP_005261192 XM_005261136 XP_005261193 XM_005261137 XP_005261194 XM_006724011 XP_006724074 XM_006724012 XP_006724075 XM_011529602 XP_011527904 XM_011529603 XP_011527905 NM_001002021 NP_001002021 NM_002626 NP_002617 |
| Function | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. {ECO:0000255|HAMAP-Rule:MF_03184, ECO:0000269|PubMed:22923583}. |
| Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}. |
| Top Pathways | RNA degradation, Pentose phosphate pathway, AMPK signaling pathway, Central carbon metabolism in cancer, Glucagon signaling pathway |