| Gene Symbol | DYNC1H1 |
|---|---|
| Entrez Gene | 1778 |
| Alt Symbol | DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22 |
| Species | Human |
| Gene Type | protein-coding |
| Description | dynein, cytoplasmic 1, heavy chain 1 |
| Other Description | cytoplasmic dynein 1 heavy chain 1|dynein heavy chain, cytosolic|dynein, cytoplasmic, heavy polypeptide 1 |
| Swissprots | Q14204 Q92814 Q6DKQ7 B0I1R0 Q9Y4G5 Q8WU28 |
| Accessions | AAT74625 EAW81759 EAW81760 EAW81761 EAW81762 EAW81763 EAW81764 Q14204 AB002323 BAA20783 AB290157 BAG06711 AF234785 AAF35913 AI241115 AI302138 AK023747 AK095415 AK299878 BAG61728 AL833600 BC021297 AAH21297 BC064521 AAH64521 BM976324 BP871545 BX648670 DB508175 L23958 AAA16065 U53530 AAB09727 U61737 AAC50701 NM_001376 NP_001367 |
| Function | Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. |
| Subcellular Location | Cytoplasm, cytoskeleton. |
| Top Pathways | Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection |