KDELR1

Gene Symbol KDELR1
Entrez Gene 10945
Alt Symbol ERD2, ERD2.1, HDEL, PM23
Species Human
Gene Type protein-coding
Description KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
Other Description ER lumen protein retaining receptor 1|ER lumen protein-retaining receptor 1|KDEL endoplasmic reticulum protein retention receptor 1|KDEL receptor 1|putative MAPK-activating protein PM23
Swissprots Q54A39 B2R6N4 Q8NBW7 P24390
Accessions EAW52340 EAW52341 EAW52342 EAW52343 EAW52344 EAW52345 P24390 AB097047 BAC77400 AK075185 BAC11457 AK312647 BAG35531 BC008958 AAH08958 BC018778 AAH18778 DQ891992 ABM82918 DQ895182 ABM86108 X55885 CAA39371 XM_011526358 XP_011524660 NM_006801 NP_006792
Function Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi. {ECO:0000269|PubMed:11703931}.
Subcellular Location Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000269|PubMed:14517323}; Multi-pass membrane protein {ECO:0000269|PubMed:14517323}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:14517323}; Multi-pass membrane protein {ECO:0000269|PubMed:14517323}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:14517323}.
Top Pathways Vibrio cholerae infection

KDEL receptor (FL-212) - sc-33806 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KDEL receptor (FL-212): sc-33806. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

KDEL receptor (KR-10) - sc-57347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

KDEL receptor 1/2 (A-13)-R - sc-23245-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
KDEL receptor 1/2 (A-13)-R: sc-23245-R. Western blot analysis of KDEL receptor 1/2 expression in mouse small intestine tissue extract.

KDEL receptor 1/2/3 (V-12)-R - sc-23246-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
KDEL receptor 1/2/3 (V-12)-R: sc-23246-R. Western blot analysis of KDEL receptor 1/2/3 expression in mouse small intestine tissue extract.

Anti-KDEL antibody - ab181472 from Abcam

Prices $370.00
Sizes 25 µg
Host Rabbit
Clonality Polyclonal

Anti-KDEL antibody [10C3] - ab195801 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 10C3
Immunofluorescent analysis of mouse C2C12 myoblasts transfected with wild type mouse ADAM12 labeling KDEL with ab195801.

Anti-KDEL antibody [EPR12668] - ER Marker - ab176333 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12668
Immunofluorescent staining of MCF7 cells labeling KDEL ER with ab176333 at 1/100 dilution (red). DAPI nuclear staining (blue).

Anti-KDEL antibody [EPR12668] - ER Marker (Alexa Fluor® 488) - ab184819 from Abcam

Prices $438.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12668
Overlay histogram showing HeLa cells stained with ab184819 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab184819, 1/500 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.This antibody gave a positive signal in HeLa fixed with 4% formaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-KDEL Receptor antibody - C-terminal - ab138921 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KDEL Receptor antibody - C-terminal (ab138921) at 1/100 dilution + MCF7 cell lysate at 35 µg

Anti-KDELR1 / HDEL Antibody (C-Terminus) - LS-C130330 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, AP) - LS-C215392 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, APC) - LS-C215395 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, Biotin) - LS-C215396 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, FITC) - LS-C215397 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, PE) - LS-C215399 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211, Azide-free, HRP) - LS-C215398 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa184-211) - LS-C329722 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KDELR1 / HDEL Antibody (aa185-211) - LS-C159985 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KDELR1 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The KDELR1 antibody detected the KDELR1 protein (arrow).

KDELR1 Antibody - NBP2-32053 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: KDELR1 Antibody [NBP2-32053] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islets of Langerhans.

ANTI-KDELR1(C-TERMINAL) antibody produced in rabbit - SAB1305245 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KDELR1 (C-term): <B>Cat. No. SAB1305245</B>: KDELR1 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35 μg/lane).

Anti-KDELR1 antibody produced in rabbit - HPA047440 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KDELR1: <B>Cat. No. HPA047440</B>: Immunohistochemical staining of Human pancreas shows strong cytoplasmic positivity in islets of Langerhans.

KDELR1 Antibody (OASE00113) - OASE00113 from Aviva Systems Biology

Prices $195.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal
Clone 2E7

KDELR1 Antibody (OASE00114) - OASE00114 from Aviva Systems Biology

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E7

KDELR1-Antibody-C-term - AP19130b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KDELR1 Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: 293 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

KDELR1 Antibody - C-terminal region (OAAB14684) - OAAB14684 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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