Gene Symbol | KDELR1 |
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Entrez Gene | 10945 |
Alt Symbol | ERD2, ERD2.1, HDEL, PM23 |
Species | Human |
Gene Type | protein-coding |
Description | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
Other Description | ER lumen protein retaining receptor 1|ER lumen protein-retaining receptor 1|KDEL endoplasmic reticulum protein retention receptor 1|KDEL receptor 1|putative MAPK-activating protein PM23 |
Swissprots | Q54A39 B2R6N4 Q8NBW7 P24390 |
Accessions | EAW52340 EAW52341 EAW52342 EAW52343 EAW52344 EAW52345 P24390 AB097047 BAC77400 AK075185 BAC11457 AK312647 BAG35531 BC008958 AAH08958 BC018778 AAH18778 DQ891992 ABM82918 DQ895182 ABM86108 X55885 CAA39371 XM_011526358 XP_011524660 NM_006801 NP_006792 |
Function | Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi. {ECO:0000269|PubMed:11703931}. |
Subcellular Location | Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000269|PubMed:14517323}; Multi-pass membrane protein {ECO:0000269|PubMed:14517323}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:14517323}; Multi-pass membrane protein {ECO:0000269|PubMed:14517323}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:14517323}. |
Top Pathways | Vibrio cholerae infection |
Human KDEL Receptor full length protein - ab153142 from Abcam
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KDELR1 / HDEL Antibody Blocking Peptide - LS-E6397 from LifeSpan Bioscience
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Recombinant Human KDELR1 Protein - H00010945-P01 from Novus Biologicals
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KDELR1-Antibody-C-term-Blocking-Peptide - BP19130b from Abgent, a WuXi AppTec company
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KDEL Receptor 1 / KDELR1 - H00010945-P01-10 from Acris Antibodies
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KDEL Receptor 1 / KDELR1 - H00010945-P01-25 from Acris Antibodies
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KDEL Receptor 1 / KDELR1 - TP305880 from Acris Antibodies
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KDELR1 Protein - NBP2-32053PEP from Novus Biologicals
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KDELR1 Peptide, Human - M34GP08036H from Creative Peptides
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ER lumen protein retaining receptor 1 (KDELR1), Recombinant Protein - MBS964124 from MyBioSource
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ER lumen protein retaining receptor 1 (KDELR1), Recombinant Protein - MBS7017835 from MyBioSource
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KDELR1 fusion protein - Ag26298 from Proteintech Group
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