FERMT3

Gene Symbol FERMT3
Entrez Gene 83706
Alt Symbol KIND3, MIG-2, MIG2B, UNC112C, URP2, URP2SF
Species Human
Gene Type protein-coding
Description fermitin family member 3
Other Description MIG2-like protein|UNC-112 related protein 2|fermitin family homolog 3|kindlin 3|unc-112-related protein 2
Swissprots Q9BT48 Q8N207 Q8IUA1 Q86UX7
Accessions EAW74199 EAW74200 Q86UX7 AK093719 BAC04220 AL560215 AY093951 AAM19736 AY093952 AAM19737 BC004347 AAH04347 BC013366 AAH13366 BC015584 AAH15584 BG491422 L25343 XM_011545294 XP_011543596 XM_011545295 XP_011543597 XM_011545296 XP_011543598 NM_031471 NP_113659 NM_178443 NP_848537
Function Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity). {ECO:0000250}.
Subcellular Location Cell projection, podosome {ECO:0000250}. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. {ECO:0000250}.
Tissue Specificity Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies. {ECO:0000269|PubMed:12697302, ECO:0000269|PubMed:12886250}.

Kindlin-3 Antibody - 13843 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Kindlin-3 Antibody.

Kindlin-3 (N-12) - sc-133428 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Kindlin-3 (T-12) - sc-133429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-URP2 antibody - ab126900 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-URP2 antibody (ab126900) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-URP2 antibody - ab67928 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-URP2 antibody (ab67928) at 1/500 dilutionLane 1 : URP2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-URP2 antibody - ab77050 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-URP2 antibody (ab77050) at 1 µg/mlLane 2 : Anti-URP2 antibody (ab77050) at 2 µg/mlLane 1 : rat spleen lysateLane 2 : rat spleen lysateLysates/proteins at 15 µg per lane.

Anti-URP2 antibody [3D6] - ab173416 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D6
IHC image of URP2 staining in Human normal spleen formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab173416, 0.1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-URP2 / FERMT3 Antibody - LS-C132798 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-URP2 / FERMT3 Antibody - LS-C307520 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-URP2 / FERMT3 Antibody - LS-C310357 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-URP2 / FERMT3 Antibody (aa645-655) - LS-C108134 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
FERMT3 antibody (1 ug/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-URP2 / FERMT3 Antibody - LS-C155470 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Gastric ca, using URP2 antibody at 1:500 dilution.

Anti-URP2 / FERMT3 Antibody (C-Terminus) IHC-plus™ - LS-B3808 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FERMT3 / URP2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3808 concentration 5 ug/ml.

FERMT3/URP2 Antibody - AF7004 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human platelets. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human FERMT3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7004) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for FERMT3 at approximately 80 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

FERMT3/URP2 Antibody - NBP2-20821 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: URP2 Antibody [NBP2-20821] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.

FERMT3/URP2 Antibody - NBP1-52287 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: URP2 Antibody [NBP1-52287] - Staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

FERMT3/URP2 Antibody - H00083706-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: URP2 Antibody [H00083706-B01P] - analysis of URP2 expression in transfected 293T cell line by URP2 MaxPab polyclonal antibody. Lane 1: URP2 transfected lysate (72.93 KDa). Lane 2: Non-transfected lysate.

FERMT3/URP2 Antibody - NBP1-76349 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FERMT3/URP2 Antibody [NBP1-76349] - Analysis of KINDLIN3 in rat spleen lysate with KINDLIN3 antibody at (A) 1 and (B) 2 ug/mL.

FERMT3/URP2 Antibody - NBP1-51974 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: FERMT3/URP2 Antibody [NBP1-51974] - Analysis of URP2 in Human Peripheral Blood Mononucleocytes lysate (35ug protein in RIPA buffer) using NBP1-51974 at 1ug/ml. Primary incubation was 1 hour. Detected bychemiluminescence.

FERMT3/URP2 Antibody - H00083706-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

URP2 Polyclonal Antibody - bs-13738R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

URP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13738R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

URP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13738R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

URP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13738R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

URP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13738R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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