FERMT3

Gene Symbol FERMT3
Entrez Gene 83706
Alt Symbol KIND3, MIG-2, MIG2B, UNC112C, URP2, URP2SF
Species Human
Gene Type protein-coding
Description fermitin family member 3
Other Description MIG2-like protein|UNC-112 related protein 2|fermitin family homolog 3|kindlin 3|unc-112-related protein 2
Swissprots Q9BT48 Q8N207 Q8IUA1 Q86UX7
Accessions EAW74199 EAW74200 Q86UX7 AK093719 BAC04220 AL560215 AY093951 AAM19736 AY093952 AAM19737 BC004347 AAH04347 BC013366 AAH13366 BC015584 AAH15584 BG491422 L25343 XM_011545294 XP_011543596 XM_011545295 XP_011543597 XM_011545296 XP_011543598 NM_031471 NP_113659 NM_178443 NP_848537
Function Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity). {ECO:0000250}.
Subcellular Location Cell projection, podosome {ECO:0000250}. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. {ECO:0000250}.
Tissue Specificity Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies. {ECO:0000269|PubMed:12697302, ECO:0000269|PubMed:12886250}.

Human FERMT3 Gene cDNA Clone - orb143164 from Biorbyt

Prices $366.00
Sizes 10 μg
Species Human

FERMT3 - MBS1268585 from MyBioSource

Species Human
Accession BC004347

Human FERMT3 ORF Clone(NM_031471.5) - CDCL163417 from Creative Biomart

Species Human
Accession NM_031471.5

Human FERMT3 ORF Clone(NM_031471.5) - CDCL163418 from Creative Biomart

Species Human
Accession NM_031471.5

Human FERMT3 ORF Clone (BC004347) - CDCS416101 from Creative biogene

Species Human
Accession Q86UX7

Human FERMT3 ORF clone (BC004347) - CDCB158514 from Creative biogene

Species Human
Search more