FERMT3

Gene Symbol FERMT3
Entrez Gene 83706
Alt Symbol KIND3, MIG-2, MIG2B, UNC112C, URP2, URP2SF
Species Human
Gene Type protein-coding
Description fermitin family member 3
Other Description MIG2-like protein|UNC-112 related protein 2|fermitin family homolog 3|kindlin 3|unc-112-related protein 2
Swissprots Q9BT48 Q8N207 Q8IUA1 Q86UX7
Accessions EAW74199 EAW74200 Q86UX7 AK093719 BAC04220 AL560215 AY093951 AAM19736 AY093952 AAM19737 BC004347 AAH04347 BC013366 AAH13366 BC015584 AAH15584 BG491422 L25343 XM_011545294 XP_011543596 XM_011545295 XP_011543597 XM_011545296 XP_011543598 NM_031471 NP_113659 NM_178443 NP_848537
Function Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity). {ECO:0000250}.
Subcellular Location Cell projection, podosome {ECO:0000250}. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. {ECO:0000250}.
Tissue Specificity Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies. {ECO:0000269|PubMed:12697302, ECO:0000269|PubMed:12886250}.

Kindlin-3 CRISPR/Cas9 KO Plasmid (h) - sc-408381 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 HDR Plasmid (h) - sc-408381-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 Double Nickase Plasmid (h) - sc-408381-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 Double Nickase Plasmid (h2) - sc-408381-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 CRISPR Activation Plasmid (h) - sc-408381-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 CRISPR Activation Plasmid (h2) - sc-408381-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 Lentiviral Activation Particles (h) - sc-408381-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 Lentiviral Activation Particles (h2) - sc-408381-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Kindlin-3 siRNA (h) - sc-96761 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kindlin-3 shRNA Plasmid (h) - sc-96761-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Kindlin-3 shRNA (h) Lentiviral Particles - sc-96761-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8627 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8627 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FERMT3 siRNA (Human) - CRJ3172 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FERMT3 - MBS8220323 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FERMT3 (NM_178443.2) - SHH294125 from Creative biogene

Category siRNA
Species Reactivities Human

Human FERMT3 siRNA - orb273673 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FERMT3 shRNA Plasmid (Human) - CHJ3172 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FERMT3 miRNA 3'UTR clone - MiUTR3H-09557 from Creative biogene

Species Reactivities Human

FERMT3 miRNA 3'UTR clone - MiUTR3H-09558 from Creative biogene

Species Reactivities Human
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