Gene Symbol | PLA2G4C |
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Entrez Gene | 8605 |
Alt Symbol | CPLA2-gamma |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group IVC (cytosolic, calcium-independent) |
Other Description | cytosolic phospholipase A2 gamma|phospholipase A2 group IVC |
Swissprots | O75457 B2RB71 Q6IBI8 Q9UP65 B4DI40 Q9UG68 |
Accessions | AAR25453 BAC87744 BAC87745 BAC87746 EAW52311 EAW52312 EAW52313 EAW52314 EAW52315 Q9UP65 AF058921 AAC32823 AF065214 AAC78835 AK022440 AK124241 AK126152 AK295400 BAG58352 AK314524 BAG37118 AL050193 CAB43312 BC017956 AAH17956 BC063416 AAH63416 CR456816 CAG33097 XM_011527431 XP_011525733 XM_011527432 XP_011525734 XM_011527433 XP_011525735 XM_011527434 XP_011525736 NM_001159322 NP_001152794 NM_001159323 NP_001152795 NM_003706 NP_003697 |
Function | Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. {ECO:0000269|PubMed:10085124}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:10085124}; Lipid-anchor {ECO:0000269|PubMed:10085124}. |
Tissue Specificity | Highly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:9705332}. |
Top Pathways | Long-term depression, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels |
group IVC sPLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-411191 from Santa Cruz Biotechnology
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group IVC sPLA 2 HDR Plasmid (h) - sc-411191-HDR from Santa Cruz Biotechnology
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group IVC sPLA 2 Double Nickase Plasmid (h) - sc-411191-NIC from Santa Cruz Biotechnology
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group IVC sPLA 2 Double Nickase Plasmid (h2) - sc-411191-NIC-2 from Santa Cruz Biotechnology
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group IVC sPLA 2 CRISPR Activation Plasmid (h) - sc-411191-ACT from Santa Cruz Biotechnology
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group IVC sPLA 2 CRISPR Activation Plasmid (h2) - sc-411191-ACT-2 from Santa Cruz Biotechnology
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group IVC sPLA 2 Lentiviral Activation Particles (h) - sc-411191-LAC from Santa Cruz Biotechnology
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group IVC sPLA 2 Lentiviral Activation Particles (h2) - sc-411191-LAC-2 from Santa Cruz Biotechnology
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group IVC sPLA 2 siRNA (h) - sc-97603 from Santa Cruz Biotechnology
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group IVC sPLA 2 shRNA Plasmid (h) - sc-97603-SH from Santa Cruz Biotechnology
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group IVC sPLA 2 shRNA (h) Lentiviral Particles - sc-97603-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU156211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16896 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16896 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04036 from Sigma-Aldrich
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PLA2G4C siRNA (Human) - CRH5653 from Cohesion Biosciences
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Human PLA2G4C siRNA - orb266155 from Biorbyt
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PLA2G4C shRNA Plasmid (Human) - CHH5653 from Cohesion Biosciences
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PLA2G4C miRNA 3'UTR clone - MiUTR3H-06104 from Creative biogene
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PLA2G4C miRNA 3'UTR clone - MiUTR3H-06105 from Creative biogene
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PLA2G4C miRNA 3'UTR clone - MiUTR3H-06106 from Creative biogene
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