Gene Symbol |
ORC4
|
Entrez Gene |
529245
|
Alt Symbol |
ORC4L
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
origin recognition complex, subunit 4
|
Other Description |
origin recognition complex subunit 4
|
Swissprots |
Q2YDI2
|
Accessions |
DAA32685 Q2YDI2 BC110211 AAI10212 XM_005202444 XP_005202501 XM_010801983 XP_010800285 NM_001046301 NP_001039766
|
Function |
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|
Top Pathways |
Cell cycle
|