INSIG2

Gene Symbol	INSIG2
Entrez Gene	51141
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	insulin induced gene 2
Other Description	INSIG-2|INSIG2 membrane protein|insulin induced protein 2|insulin-induced gene 2 protein
Swissprots	Q9Y5U4 Q8TBI8 A8K5W8
Accessions	AAX93280 EAW95199 EAW95200 Q9Y5U4 AF125392 AAD43048 AF527632 AAN28333 AK021692 AK291433 BAF84122 AK298599 BAG60785 AL080184 BC022475 AAH22475 BX647805 XM_005263690 XP_005263747 XM_011511292 XP_011509594 NM_016133 NP_057217
Function	Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR. {ECO:0000269|PubMed:12242332, ECO:0000269|PubMed:16606821}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12242332}; Multi-pass membrane protein {ECO:0000269|PubMed:12242332}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-INSIG2-cDNA-Clone - DC05269 from Abgent, a WuXi AppTec company Prices $303.75 Sizes 10 µg Species Human Accession BC022475

INSIG2 - MBS1266919 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022475

Human INSIG2 cDNA clone(NM_016133.2) - CDFG000165 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 ORF Clone(NM_016133.2) - CDCL167288 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 ORF Clone(NM_016133.2) - CDCL167289 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 ORF Clone(NM_016133.2) - CDCR300644 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 ORF Clone(NM_016133.2) - CDCR300645 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 ORF Clone(NM_016133.2) - CDCR300646 from Creative Biomart Species Human Accession NM_016133.2

Human INSIG2 Gene ORF cDNA clone in cloning vector - HG16273-G from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG16273-NF from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid - HG16273-UT from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG16273-CF from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG16273-NM from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG16273-CM from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-His tag - HG16273-CH from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG16273-CY from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, N-His tag - HG16273-NH from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG16273-ACG from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG16273-ACR from Sino Biological Species Human

Human INSIG2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG16273-NY from Sino Biological Species Human

Human INSIG2 ORF Clone(NM_016133.2) - CDCR300644 from Creative biogene Species Human

Human INSIG2 ORF Clone (BC022475) - CDCS418782 from Creative biogene Species Human Accession Q9Y5U4

Human INSIG2 cDNA Clone(NM_016133.2) - CDFG000165 from Creative biogene Species Human

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