Gene Symbol | DGKK |
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Entrez Gene | 139189 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | diacylglycerol kinase, kappa |
Other Description | 142 kDa diacylglycerol kinase|DAG kinase kappa|DGK-kappa|diacylglycerol kinase kappa|diglyceride kinase kappa |
Swissprots | Q5KSL6 B2RP91 |
Accessions | CCQ43037 EAW89919 Q5KSL6 AB183864 BAD86792 AI591038 BC137319 AAI37320 BC137320 AAI37321 DB728104 NM_001013742 NP_001013764 |
Function | Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). {ECO:0000269|PubMed:16210324}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16210324}. Membrane {ECO:0000269|PubMed:16210324}; Peripheral membrane protein {ECO:0000269|PubMed:16210324}. |
Tissue Specificity | Expressed in testis, and to a lesser extent in placenta. {ECO:0000269|PubMed:16210324}. |
Top Pathways | Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system |
DGK-κ siRNA (h) - sc-91229 from Santa Cruz Biotechnology
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DGK-κ shRNA Plasmid (h) - sc-91229-SH from Santa Cruz Biotechnology
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DGK-κ shRNA (h) Lentiviral Particles - sc-91229-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7185 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7185 from Sigma-Aldrich
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DGKK siRNA (Human) - CRJ5245 from Cohesion Biosciences
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DGKK RNAi - H00139189-R02 from Novus Biologicals
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DGKK - MBS828585 from MyBioSource
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shRNA set against Human Dgkk (NM_001013742.2) - SHH277521 from Creative biogene
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Human DGKK siRNA - orb275746 from Biorbyt
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DGKK shRNA Plasmid (Human) - CHJ5245 from Cohesion Biosciences
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DGKK miRNA 3'UTR clone - MiUTR4H-TG11065 from Creative biogene
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