Gene Symbol | PLD2 |
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Entrez Gene | 5338 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase D2 |
Other Description | PLD1C|choline phosphatase 2|hPLD2|phosphatidylcholine-hydrolyzing phospholipase D2 |
Swissprots | O14939 Q96BY3 O43580 O43540 Q6PGR0 O43579 I3L2C9 |
Accessions | EAW90404 EAW90405 EAW90406 O14939 AB209374 BAD92611 AF033850 AAD04197 AF035483 AAC24498 AF038440 AAB96655 AF038441 AAB96656 AK304246 BAH14141 AK314797 AM393149 CAL38027 AM393150 CAL38028 AM393159 CAL38037 AM393603 CAL38479 AY178289 AAO21120 BC015033 AAH15033 BC056871 AAH56871 DA390950 DC407587 XM_005256695 XP_005256752 XM_005256696 XP_005256753 XM_011523941 XP_011522243 XM_011523942 XP_011522244 NM_001243108 NP_001230037 NM_002663 NP_002654 |
Function | May have a role in signal-induced cytoskeletal regulation and/or endocytosis. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Sphingolipid signaling pathway, Choline metabolism in cancer, cAMP signaling pathway, Glutamatergic synapse, Endocytosis |
PC-PLD2 CRISPR/Cas9 KO Plasmid (h) - sc-402056 from Santa Cruz Biotechnology
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PC-PLD2 HDR Plasmid (h) - sc-402056-HDR from Santa Cruz Biotechnology
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PC-PLD2 Double Nickase Plasmid (h) - sc-402056-NIC from Santa Cruz Biotechnology
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PC-PLD2 Double Nickase Plasmid (h2) - sc-402056-NIC-2 from Santa Cruz Biotechnology
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PC-PLD2 CRISPR Activation Plasmid (h) - sc-402056-ACT from Santa Cruz Biotechnology
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PC-PLD2 CRISPR Activation Plasmid (h2) - sc-402056-ACT-2 from Santa Cruz Biotechnology
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PC-PLD2 Lentiviral Activation Particles (h) - sc-402056-LAC from Santa Cruz Biotechnology
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PC-PLD2 Lentiviral Activation Particles (h2) - sc-402056-LAC-2 from Santa Cruz Biotechnology
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PC-PLD2 siRNA (h) - sc-44001 from Santa Cruz Biotechnology
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PC-PLD2 shRNA Plasmid (h) - sc-44001-SH from Santa Cruz Biotechnology
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PC-PLD2 shRNA (h) Lentiviral Particles - sc-44001-V from Santa Cruz Biotechnology
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Phospholipase D2 RNAi - H00005338-R01 from Novus Biologicals
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MISSION® esiRNA - EHU154301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16937 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16937 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04678 from Sigma-Aldrich
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PLD2 siRNA (Human) - CRH3578 from Cohesion Biosciences
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PLD2 shRNA Plasmid (Human) - CHH3578 from Cohesion Biosciences
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PLD2 miRNA 3'UTR clone - MiUTR3H-04935 from Creative biogene
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