| Gene Symbol | SLC25A6 |
|---|---|
| Entrez Gene | 293 |
| Alt Symbol | 2, 3, AAC3, ANT, ANT 2, ANT 3, ANT3, ANT3Y |
| Species | Human |
| Gene Type | protein-coding |
| Description | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| Other Description | ADP,ATP carrier protein|ADP,ATP carrier protein 3|ADP,ATP carrier protein, liver|ADP/ATP translocase 3|ADP/ATP translocator of liver|adenine nucleotide translocator 3|solute carrier family 25 member 6 |
| Swissprots | P12236 Q96C49 |
| Accessions | EAW98680 P12236 AB209822 BAD93059 AF076617 AF091236 AAC61590 AK054789 AK312336 BAG35257 AY007135 AAG01998 BC007295 AAH07295 BC007850 AAH07850 BC008737 AAH08737 BC008935 AAH08935 BC013256 BC014775 AAH14775 BC031912 AAH31912 BC035469 CB150341 CR457400 CAG33681 DQ891478 ABM82404 DQ894667 ABM85593 J03592 AAA36750 NM_001636 NP_001627 |
| Function | Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. {ECO:0000269|PubMed:15033708}. |
| Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. {ECO:0000250}. |
| Top Pathways | Huntington's disease, Calcium signaling pathway, HTLV-I infection, Influenza A, cGMP-PKG signaling pathway |