ABCG1

Gene Symbol ABCG1
Entrez Gene 9619
Alt Symbol ABC8, WHITE1
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family G (WHITE), member 1
Other Description ABC transporter 8|ATP-binding cassette sub-family G member 1|ATP-binding cassette transporter 8|ATP-binding cassette transporter member 1 of subfamily G|homolog of Drosophila white|white protein homolog (ATP-binding cassette transporter 8)
Swissprots Q9BXK9 Q9BXK7 Q9BXL2 Q96L76 Q9BXL3 Q86SU8 Q9BXK8 Q9BXL0 Q9BXL4 P45844 Q9BXL1 Q9BXK6
Accessions AAK28833 AAK28834 AAK28835 AAK28836 AAK28837 BAA95530 BAB13728 CAC00730 EAX09574 EAX09575 P45844 AF038175 AAB97364 AF086547 AF323660 AAK28838 AF323661 AAK28839 AF323662 AAK28840 AF323663 AAK28841 AF323664 AAK28842 AK092959 AK292152 BAF84841 AK298491 BAG60699 AL355688 AL355711 AL833689 AY048757 AAL06598 BC029158 AAH29158 BX537588 DQ891343 ABM82269 EU176570 ABW03371 EU832827 ACE87838 GQ129336 ACT64470 X91249 CAA62631 XM_011529806 XP_011528108 XM_011529807 XP_011528109 NM_004915 NP_004906 NM_016818 NP_058198 NM_207174 NP_997057 NM_207627 NP_997510 NM_207628 NP_997511 NM_207629 NP_997512 NM_207630
Function Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:22042635}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22042635}; Multi-pass membrane protein {ECO:0000269|PubMed:22042635}. Golgi apparatus membrane {ECO:0000269|PubMed:22042635}; Multi-pass membrane protein {ECO:0000269|PubMed:22042635}. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.
Tissue Specificity Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease. {ECO:0000269|PubMed:11350058}.
Top Pathways ABC transporters

ABCG1 (E-20) - sc-11150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCG1 (E-20): sc-11150. Immunofluorescence staining of methanol-fixed c4 cells showing membrane and cytoplasmic localization.

ABCG1 (H-65) - sc-20795 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ABCG1 (H-65): sc-20795. Western blot analysis of ABCG1 expression in Hep G2 (A) and Jurkat (B) whole cell lysates.

ABCG1 (L-18) - sc-21808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ABCG1 antibody - ab106263 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lanes 1 - 5 : Anti-ABCG1 antibody (ab106263) at 1/1000 dilutionLane 6 : Anti-GNPDA2 antibody (ab106363) at 1/1000 dilutionLane 1 : PC-3M1B8Lane 2 : Human fetal spleen lysateLane 3 : Human fetal brain lysateLane 4 : Human fetal kidney lysateLane 5 : Human fetal lung lysateLane 6 : Human fetal thymus lysate

Anti-ABCG1 antibody - ab135040 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-ABCG1 antibody (ab135040) at 1/1000 dilution + HepG2 total cell extracts

Anti-ABCG1 antibody - ab36969 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABCG1 antibody (ab36969)Lane 1 : Positive ABCG1 control detected in mouse peritoneal macrophages (40 µg) Lane 2 : 10 µM 22-(R)-hydocholesterol treated mouse peritoneal macrophages (40 µg) Lane 3 : 100 nM TO901713 (LXRa ligand) treated mouse peritoneal macrophages (40 µg) Lane 4 : 500 nM TO91713 (LXRa ligand) treated mouse peritoneal macrophages (40 µg) developed using the ECL technique

Anti-ABCG1 Antibody (C-Terminus) - LS-C34776 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa300-400, Biotin) - LS-C83841 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal) - LS-C63393 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa300-400, HRP) - LS-C83842 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa300-400) - LS-C83843 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal, HRP) - LS-C122571 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal, Biotin) - LS-C122570 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal, DY650) - LS-C142183 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal, DY488) - LS-C142184 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (Internal, DY550) - LS-C142185 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa79-312, Biotin) - LS-C298880 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa79-312, FITC) - LS-C305296 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (clone EP1366Y) - LS-C49901 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1366Y
IHC of paraffin-embedded human cervical carcinoma using anti-ABCG1 antibody.

Anti-ABCG1 Antibody (clone 2H8) - LS-C139134 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H8
Detection limit for recombinant GST tagged ABCG1 is 1 ng/ml as a capture antibody.

Anti-ABCG1 Antibody (aa633-678) - LS-C313655 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa627-647) - LS-C313008 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of ABCG1 antibody. Lane 1: U87 Cell Lysate. Lane 2: SMMC Cell Lysate. Lane 3: HELA Cell Lysate. Lane 4: COLO320 Cell Lysate. Lane 5: MCF-7 Cell Lysate.

Anti-ABCG1 Antibody - LS-C333240 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (N-Terminus) - LS-C347597 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCG1 Antibody (aa300-400) IHC-plus™ - LS-B507 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ABCG1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B507 concentration 20 ug/ml.
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