Gene Symbol | ABCG1 |
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Entrez Gene | 9619 |
Alt Symbol | ABC8, WHITE1 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family G (WHITE), member 1 |
Other Description | ABC transporter 8|ATP-binding cassette sub-family G member 1|ATP-binding cassette transporter 8|ATP-binding cassette transporter member 1 of subfamily G|homolog of Drosophila white|white protein homolog (ATP-binding cassette transporter 8) |
Swissprots | Q9BXK9 Q9BXK7 Q9BXL2 Q96L76 Q9BXL3 Q86SU8 Q9BXK8 Q9BXL0 Q9BXL4 P45844 Q9BXL1 Q9BXK6 |
Accessions | AAK28833 AAK28834 AAK28835 AAK28836 AAK28837 BAA95530 BAB13728 CAC00730 EAX09574 EAX09575 P45844 AF038175 AAB97364 AF086547 AF323660 AAK28838 AF323661 AAK28839 AF323662 AAK28840 AF323663 AAK28841 AF323664 AAK28842 AK092959 AK292152 BAF84841 AK298491 BAG60699 AL355688 AL355711 AL833689 AY048757 AAL06598 BC029158 AAH29158 BX537588 DQ891343 ABM82269 EU176570 ABW03371 EU832827 ACE87838 GQ129336 ACT64470 X91249 CAA62631 XM_011529806 XP_011528108 XM_011529807 XP_011528109 NM_004915 NP_004906 NM_016818 NP_058198 NM_207174 NP_997057 NM_207627 NP_997510 NM_207628 NP_997511 NM_207629 NP_997512 NM_207630 |
Function | Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:22042635}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22042635}; Multi-pass membrane protein {ECO:0000269|PubMed:22042635}. Golgi apparatus membrane {ECO:0000269|PubMed:22042635}; Multi-pass membrane protein {ECO:0000269|PubMed:22042635}. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes. |
Tissue Specificity | Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease. {ECO:0000269|PubMed:11350058}. |
Top Pathways | ABC transporters |
Human ABCG1 full length protein - ab153003 from Abcam
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Human ABCG1 protein fragment - ab153004 from Abcam
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ABCG1 Antibody Blocking Peptide - LS-E8266 from LifeSpan Bioscience
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ABCG1 Antibody Blocking Peptide - LS-E8267 from LifeSpan Bioscience
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ABCG1 Blocking Peptide - NB400-132PEP from Novus Biologicals
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Recombinant Human ABCG1 Protein - H00009619-Q01 from Novus Biologicals
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Recombinant Human ABCG1 Protein - H00009619-P01 from Novus Biologicals
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ABCG1-Antibody-Center-Blocking-Peptide - BP6529c from Abgent, a WuXi AppTec company
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ABCG1-Antibody-N-term-Blocking-Peptide - BP6529a from Abgent, a WuXi AppTec company
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ABCG1 Blocking Peptide - abx063604 from Abbexa
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Human ABCG1 Protein - abx065475 from Abbexa
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ABCG1 - H00009619-P01-10 from Acris Antibodies
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ABCG1 - H00009619-P01-25 from Acris Antibodies
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ABCG1 - H00009619-Q01-10 from Acris Antibodies
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ABCG1 - H00009619-Q01-25 from Acris Antibodies
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ATP Binding Cassette Transporter G1 (ABCG1), Human - 20-7624 from ARP American Research Products
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ABCG1 fusion protein - Ag4479 from Proteintech Group
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ABCG1 fusion protein - Ag17329 from Proteintech Group
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Recombinant Human ABCG1, GST-tagged - ABCG1-9228H from Creative Biomart
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Recombinant Human ABCG1, His-tagged - ABCG1-3697H from Creative Biomart
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Recombinant ATP Binding Cassette Transporter G1 (ABCG1) - RPB288Hu01 from Uscn Life Science Inc.
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ABCG1 Blocking Peptide - CBP2410 from Cohesion Biosciences
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ABCG1 Peptide - BS5596P from Bioworld Technology
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Recombinant ATP Binding Cassette Transporter G1 (ABCG1) - RPB288Hu01 from Cloud-clone
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ABCG1 (transcript variant 2) - TP306478 from Acris Antibodies
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