Gene Symbol | CLEC10A |
---|---|
Entrez Gene | 10462 |
Alt Symbol | CD301, CLECSF13, CLECSF14, HML, HML2, MGL |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 10, member A |
Other Description | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived)|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived)|C-type lectin domain family 10 member A|macrophage lectin 2 (calcium dependent) |
Swissprots | Q8IUN9 Q6PIW3 Q14538 A8K8J8 |
Accessions | EAW90265 EAW90266 EAW90267 Q8IUN9 AK291975 BAF84664 AK292363 BAF85052 AL546075 BC027858 AAH27858 BC039011 AAH39011 BI910082 BM974488 BU687211 D50532 BAA09101 XM_005256412 XP_005256469 XM_011523613 XP_011521915 XM_011523614 XP_011521916 XM_011523615 XP_011521917 NM_006344 NP_006335 NM_182906 NP_878910 |
Function | Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. {ECO:0000269|PubMed:8598452}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |